We demonstrated that, in contrast to classical opioid receptors, ACKR3 doesn't trigger classical G protein signaling and isn't modulated because of the classical prescription or analgesic opioids, such as morphine, fentanyl, or buprenorphine, or by nonselective opioid antagonists including naloxone. As an alternative, we established that LIH383, an ACKR3-selective https://georges470uql8.blog4youth.com/profile