B lymphocytes are subject to elimination following strong BCR ligation in the absence of appropriate second signals. and this mechanism mediates substantial cell losses during late differentiation steps in the bone marrow and periphery. Mature B cells may also be eliminated through this mechanism as well as through normal turnover. but the population containing mature cells destined f... https://www.chiggate.com/color-charm-12n-1200-high-lift-blonde-1-4oz-online-now/