Conolidine’s analgesic consequences stem from its interaction with non-opioid pain pathways. Unlike opioids, which bind to µ-opioid receptors in the central anxious procedure, conolidine modulates alternate molecular targets. A Science Improvements review discovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability.... https://thenewpainkillerconolidin64298.theideasblog.com/38343910/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers